Issue 43, 2012

Cu(ii)-promoted three-component coupling sequence for the efficient synthesis of substituted quinolines

Abstract

The copper-promoted three-component coupling sequence for substituted quinoline formation from aldehydes, anilines and acetone is described. Various 2-arylquinolines were selectively obtained in good yields under mild conditions. The reaction tolerated a wide range of functionalities.

Graphical abstract: Cu(ii)-promoted three-component coupling sequence for the efficient synthesis of substituted quinolines

Supplementary files

Article information

Article type
Communication
Submitted
30 Jul 2012
Accepted
10 Sep 2012
First published
12 Sep 2012

Org. Biomol. Chem., 2012,10, 8593-8596

Cu(II)-promoted three-component coupling sequence for the efficient synthesis of substituted quinolines

F. Xiao, W. Chen, Y. Liao and G. Deng, Org. Biomol. Chem., 2012, 10, 8593 DOI: 10.1039/C2OB26484F

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