Intramolecular nitrone dipolar cycloadditions: control of regioselectivity and synthesis of naturally-occurring spirocyclic alkaloids†
Abstract
The intramolecular nitrone dipolar
* Corresponding authors
a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
b GlaxoSmithKline Research and Development, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK
c
School of Chemistry, Bio21 Institute, University of Melbourne, Vic. 3010, Australia
E-mail:
aholmes@unimelb.edu.au
d
CSIRO Materials Science & Engineering, Ian Wark Laboratory, Bayview Avenue, Clayton, VIC 3168, Australia
E-mail:
annabella.newton@csiro.au
e Novartis Horsham Research Centre, Wimblehurst Road, Horsham RH12 4AB, UK
f Syngenta, Jealott's Hill International Research Centre, Bracknell RG42 6EY, UK
The intramolecular nitrone dipolar
A. J. Hodges, J. P. Adams, A. D. Bond, A. B. Holmes, N. J. Press, S. D. Roughley, J. H. Ryan, S. Saubern, C. J. Smith, M. D. Turnbull and A. F. Newton, Org. Biomol. Chem., 2012, 10, 8963 DOI: 10.1039/C2OB26333E
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