Issue 38, 2012

The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

Abstract

The Kulinkovich cyclopropanation reaction provides a flexible and convenient method for the synthesis of cyclopropanols. Together with the diverse chemistry of the cyclopropanol unit, it offers access to a wide range of functionalised unsaturated and saturated compounds. The successful use in the synthesis of natural compounds is outlined in this perspective.

Graphical abstract: The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

Article information

Article type
Perspective
Submitted
05 Jun 2012
First published
24 Jul 2012

Org. Biomol. Chem., 2012,10, 7649-7665

The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

I. Haym and M. A. Brimble, Org. Biomol. Chem., 2012, 10, 7649 DOI: 10.1039/C2OB26082D

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