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Issue 38, 2012
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The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

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Abstract

The Kulinkovich cyclopropanation reaction provides a flexible and convenient method for the synthesis of cyclopropanols. Together with the diverse chemistry of the cyclopropanol unit, it offers access to a wide range of functionalised unsaturated and saturated compounds. The successful use in the synthesis of natural compounds is outlined in this perspective.

Graphical abstract: The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

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Article information


Submitted
05 Jun 2012
First published
24 Jul 2012

Org. Biomol. Chem., 2012,10, 7649-7665
Article type
Perspective

The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis

I. Haym and M. A. Brimble, Org. Biomol. Chem., 2012, 10, 7649
DOI: 10.1039/C2OB26082D

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