Issue 32, 2012
From the journal:

Organic & Biomolecular Chemistry

Synthesis and biological evaluation of a new triazole–oxotechnetium complex†

Olivier Martinage,a   Loïc Le Clainche,a   Bertrand Czarnya  and  Christophe Dugave‡*a  

* Corresponding authors

a CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Laboratoire de Chimie du Vivant, bâtiment 152, 91191 Gif-sur-Yvette, France
E-mail: christophe.dugave@cea.fr
Fax: +33 16908 7991
Tel: +33 16908 9938

Abstract

A new triazole oxotechnetium chelating agent was synthesized via a ‘Click-to-Chelate’ strategy. In vivo evaluation of the corresponding 99mTc complex shows that the tracer exhibits very interesting properties for molecular imaging.

Graphical abstract: Synthesis and biological evaluation of a new triazole–oxotechnetium complex

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Article information

DOI
https://doi.org/10.1039/C2OB25774B
Article type
Paper
Submitted
23 Apr 2012
Accepted
13 Jun 2012
First published
13 Jun 2012

Org. Biomol. Chem., 2012,10, 6484-6490

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Synthesis and biological evaluation of a new triazole–oxotechnetium complex

O. Martinage, L. Le Clainche, B. Czarny and C. Dugave, Org. Biomol. Chem., 2012, 10, 6484 DOI: 10.1039/C2OB25774B

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