Issue 13, 2012

Syntheses of (−)-pelletierine and (−)-homopipecolic acid

Abstract

Enantiomeric syntheses of (−)-homopipecolic acid and (−)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer–Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines.

Graphical abstract: Syntheses of (−)-pelletierine and (−)-homopipecolic acid

Supplementary files

Article information

Article type
Communication
Submitted
25 Nov 2011
Accepted
27 Jan 2012
First published
30 Jan 2012

Org. Biomol. Chem., 2012,10, 2518-2520

Syntheses of (−)-pelletierine and (−)-homopipecolic acid

W. Chiou, G. Chen, C. Kao and Y. Gao, Org. Biomol. Chem., 2012, 10, 2518 DOI: 10.1039/C2OB06984A

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