Issue 11, 2012

Interference of intrinsic curvature of DNA by DNA-intercalating agents

Abstract

It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope.

Graphical abstract: Interference of intrinsic curvature of DNA by DNA-intercalating agents

Supplementary files

Article information

Article type
Communication
Submitted
28 Oct 2011
Accepted
12 Jan 2012
First published
12 Jan 2012

Org. Biomol. Chem., 2012,10, 2227-2230

Interference of intrinsic curvature of DNA by DNA-intercalating agents

H. K. Tan, D. Li, R. K. Gray, Z. Yang, M. T. T. Ng, H. Zhang, J. M. R. Tan, S. H. Hiew, J. Y. Lee and T. Li, Org. Biomol. Chem., 2012, 10, 2227 DOI: 10.1039/C2OB06811G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements