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Issue 3, 2012
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Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

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Abstract

Amorphous nickel powder (Ni0) was utilised as a catalyst under mild, aqueous, basic conditions for enhancing the sodium borohydride-mediated reduction of C–N multiple bonds such as oximes, imines, hydrazones and nitriles to produce the corresponding amines in good to excellent yields.

Graphical abstract: Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

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Publication details

The article was received on 28 Aug 2011, accepted on 30 Sep 2011 and first published on 03 Oct 2011


Article type: Paper
DOI: 10.1039/C1OB06471A
Org. Biomol. Chem., 2012,10, 663-670

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    Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

    S. Liu, Y. Yang, X. Zhen, J. Li, H. He, J. Feng and A. Whiting, Org. Biomol. Chem., 2012, 10, 663
    DOI: 10.1039/C1OB06471A

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