Issue 2, 2012
From the journal:

Organic & Biomolecular Chemistry

Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes†

Dong Wang,ab   Mingming Zhao,ab   Xiang Liu,ab   Yongxin Chen,ab   Na Liab  and  Baohua Chen*ab  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, P.R. of China
E-mail: chbh@lzu.edu.cn

b Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou, P. R. of China

Abstract

Good to excellent yields of 1,4-disubstituted 1,2,3-triazoles were obtained within 2–25 min when the Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC) reaction was carried out under solvent-free conditions, with [Cu(phen)(PPh3)2]NO3 (1mol%) as the catalyst.

Graphical abstract: Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes

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Article information

DOI
https://doi.org/10.1039/C1OB06190A
Article type
Communication
Submitted
18 Jul 2011
Accepted
23 Sep 2011
First published
26 Sep 2011

Org. Biomol. Chem., 2012,10, 229-231

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Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes

D. Wang, M. Zhao, X. Liu, Y. Chen, N. Li and B. Chen, Org. Biomol. Chem., 2012, 10, 229 DOI: 10.1039/C1OB06190A

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