Issue 15, 2012
From the journal:

Nanoscale

Highly efficient remote controlled release system based on light-driven DNA nanomachine functionalized mesoporous silica†

Yongqiang Wen,*a   Liping Xu,a   Wenqian Wang,a   Danyang Wang,a   Hongwu Dua  and  Xueji Zhang*ab  

* Corresponding authors

a Research Center for Bioengineering & Sensing Technology, University of Science and Technology Beijing, Beijing 100083, China
E-mail: wyq_wen@iccas.ac.cn

b Department of Chemistry, University of South Florida, 4202 E. Fowler Ave. CHE-205A, Tampa, Fl 33620-5250, USA
E-mail: xzhang@cas.usf. edu
Fax: +1 941-3712534

Abstract

An intelligent photoswitchable single-molecule nanomachine with DNA hairpin-loop structure was designed by the incorporation of azobenzene groups in DNA sequences, which was studied by fluorescence resonance energy transfer (FRET) and attached onto the surface of mesoporous silica. Based on the photo-induced conformational transformation of DNA, highly efficient controlled release was realized.

Graphical abstract: Highly efficient remote controlled release system based on light-driven DNA nanomachine functionalized mesoporous silica

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Article information

DOI
https://doi.org/10.1039/C2NR31101A
Article type
Communication
Submitted
04 May 2012
Accepted
13 Jun 2012
First published
18 Jun 2012

Nanoscale, 2012,4, 4473-4476

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Highly efficient remote controlled release system based on light-driven DNA nanomachine functionalized mesoporous silica

Y. Wen, L. Xu, W. Wang, D. Wang, H. Du and X. Zhang, Nanoscale, 2012, 4, 4473 DOI: 10.1039/C2NR31101A

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