Issue 12, 2012
From the journal:

Nanoscale

Multifunctional imaging probe based on gadofulleride nanoplatform†

Jun-peng Zheng,ab   Qiao-ling Liu,a   Ming-ming Zhen,ab   Feng Jiang,ab   Chun-ying Shu,*a   Chan Jin,c   Yongji Yang,c   Hisham A. Alhadlaqd  and  Chun-ru Wang*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China
E-mail: shucy@iccas.ac.cn; crwang@iccas.ac.cn

b Graduate school of CAS, Beijing 100049, P. R. China

c Institute of Biophysics, Second Military Medical University, Shanghai, 200433, China

d Dept. of Physics and Astronomy, King Saud University, Po Box 25, Riyadh 11451, Saudi Arabia

Abstract

A FAR over-expressed tumor targeting multifunctional imaging probe has been fabricated based on gadofulleride nanoplatform. The combination of highly efficient MRI contrast enhancement and sensitive fluorescence imaging along with the preferential uptake toward FAR tumor cells suggest that the obtained multifunctional imaging probe possesses complementary capabilities for anatomical resolution and detection sensitivity.

Graphical abstract: Multifunctional imaging probe based on gadofulleride nanoplatform

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Article information

DOI
https://doi.org/10.1039/C2NR30836C
Article type
Communication
Submitted
07 Apr 2012
Accepted
14 May 2012
First published
15 May 2012

Nanoscale, 2012,4, 3669-3672

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Multifunctional imaging probe based on gadofulleride nanoplatform

J. Zheng, Q. Liu, M. Zhen, F. Jiang, C. Shu, C. Jin, Y. Yang, H. A. Alhadlaq and C. Wang, Nanoscale, 2012, 4, 3669 DOI: 10.1039/C2NR30836C

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