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Issue 3, 2012
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Advances in Aspergillus secondary metabolite research in the post-genomic era

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Abstract

Covering: 2005 to 2011

This review studies the impact of whole genome sequencing on Aspergillus secondary metabolite research. There has been a proliferation of many new, intriguing discoveries since sequencing data became widely available. What is more, the genomes disclosed the surprising finding that there are many more secondary metabolite biosynthetic pathways than laboratory research had suggested. Activating these pathways has been met with some success, but many more dormant genes remain to be awakened.

Graphical abstract: Advances in Aspergillus secondary metabolite research in the post-genomic era

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Publication details

The article was received on 25 Oct 2011 and first published on 06 Jan 2012


Article type: Review Article
DOI: 10.1039/C2NP00084A
Nat. Prod. Rep., 2012,29, 351-371

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    Advances in Aspergillus secondary metabolite research in the post-genomic era

    J. F. Sanchez, A. D. Somoza, N. P. Keller and C. C. C. Wang, Nat. Prod. Rep., 2012, 29, 351
    DOI: 10.1039/C2NP00084A

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