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Issue 4, 2012
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Phenazines and cancer

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Abstract

Covering: 2000 to 2011

Phenazines are a large group of natural and synthesised nitrogen-containing heterocycles, including more than 100 different compounds of natural origin and over 6000 synthetic compounds. Many of these compounds have been investigated as potential anti-cancer agents. Despite a large number of research publications, no recent attempt to summarise and critically evaluate the experimental findings relating to the anti-cancer activity of this class of compounds has been made. The present review fills this gap in the literature and discusses both natural and synthetic phenazines with a critical focus on in vitro, in vivo and available clinical anti-cancer activities of these compounds.

Graphical abstract: Phenazines and cancer

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Publication details

The article was received on 13 Oct 2011 and first published on 15 Feb 2012


Article type: Review Article
DOI: 10.1039/C2NP00079B
Citation: Nat. Prod. Rep., 2012,29, 487-501

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    Phenazines and cancer

    A. Cimmino, A. Evidente, V. Mathieu, A. Andolfi, F. Lefranc, A. Kornienko and R. Kiss, Nat. Prod. Rep., 2012, 29, 487
    DOI: 10.1039/C2NP00079B

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