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Issue 5, 2012
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Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation

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Abstract

Covering: up to 2011

This review focuses on the recent revealing of the immunostimulatory bacterial cell wall peptidoglycan (PGN) fragments as Nod1 ligands, especially a newly developed chemical synthesis of the partial structures, fragment structures in the environment and bacterial supernatant, and the immunostimulatory activities of the Nod1 ligands.

Graphical abstract: Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation

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Article information


Submitted
10 Nov 2011
First published
28 Feb 2012

Nat. Prod. Rep., 2012,29, 568-579
Article type
Review Article

Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation

Y. Fujimoto, A. R. Pradipta, N. Inohara and K. Fukase, Nat. Prod. Rep., 2012, 29, 568
DOI: 10.1039/C2NP00091A

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