Jump to main content
Jump to site search

Issue 20, 2012
Previous Article Next Article

Semi-autonomous liquid handling via on-chip pneumatic digital logic

Author affiliations

Abstract

This report presents a liquid-handling chip capable of executing metering, mixing, incubation, and wash procedures largely under the control of on-board pneumatic circuitry. The only required inputs are four static selection lines to choose between the four machine states, and one additional line for power. State selection is simple: constant application of vacuum to an input causes the device to execute one of its four liquid handling operations. Programmed control of 31 valves, including fast coordinated cycling for peristaltic pumping, is accomplished by pneumatic digital logic circuits built out of microfluidic valves and channels rather than electronics, eliminating the need for the off-chip control machinery that is typically required for integrated microfluidics.

Graphical abstract: Semi-autonomous liquid handling via on-chip pneumatic digital logic

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Apr 2012, accepted on 23 Aug 2012 and first published on 11 Sep 2012


Article type: Paper
DOI: 10.1039/C2LC40466D
Citation: Lab Chip, 2012,12, 3991-3994

  •   Request permissions

    Semi-autonomous liquid handling via on-chip pneumatic digital logic

    T. V. Nguyen, P. N. Duncan, S. Ahrar and E. E. Hui, Lab Chip, 2012, 12, 3991
    DOI: 10.1039/C2LC40466D

Search articles by author

Spotlight

Advertisements