Issue 48, 2012
From the journal:

Journal of Materials Chemistry

Co-delivery of all-trans-retinoic-acid and cisplatin(iv) prodrug based on polymer–drug conjugates for enhanced efficacy and safety

Rui Wang,†ab   Haihua Xiao,†ab   Haiqin Song,c   Yu Zhang,d   Xiuli Hu,a   Zhigang Xie,a   Yubin Huang,a   Xiabin Jing*a  and  Yuxin Li*d  

* Corresponding authors

a State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People's Republic of China

b Graduate School of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

c Department of Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China

d National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130024, People's Republic of China

Abstract

Toxic cisplatin and non-toxic all-trans-retinoic acid were combined in polymer platform to enhance drug efficacy and safety.

Graphical abstract: Co-delivery of all-trans-retinoic-acid and cisplatin(iv) prodrug based on polymer–drug conjugates for enhanced efficacy and safety

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Article information

DOI
https://doi.org/10.1039/C2JM35232J
Article type
Paper
Submitted
06 Aug 2012
Accepted
03 Oct 2012
First published
03 Oct 2012

J. Mater. Chem., 2012,22, 25453-25462

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Co-delivery of all-trans-retinoic-acid and cisplatin(IV) prodrug based on polymer–drug conjugates for enhanced efficacy and safety

R. Wang, H. Xiao, H. Song, Y. Zhang, X. Hu, Z. Xie, Y. Huang, X. Jing and Y. Li, J. Mater. Chem., 2012, 22, 25453 DOI: 10.1039/C2JM35232J

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