Jump to main content
Jump to site search

Issue 10, 2012
Previous Article Next Article

An efficient and recyclable dendritic catalyst able to dramatically decrease palladium leaching in Suzuki couplings

Author affiliations

Abstract

A series of novel monomeric and dendritic thiazolyl phosphines (generations 1 and 3) was prepared and the activity these ligands conferred to palladium in Suzuki couplings was evaluated. The heteroaryl ligands were revealed to be very efficient and were able to perform the reactions in mild conditions. Besides, their efficiency was compared to that of the corresponding triphenylphosphines. Moreover, the possibility to reuse both families of dendritic ligands was explored and the thiazolyl phosphine-based catalytic systems could be successfully recycled for five consecutive reactions without loss of activity, contrary to their triphenylphosphine counterparts. Remarkably, the palladium leaching was found to be dramatically reduced by using the dendrimer-supported thiazolylphosphines instead of the monomeric ligand and only trace amounts of metal (<0.55 ppm) could be found in the coupling product before any purification.

Graphical abstract: An efficient and recyclable dendritic catalyst able to dramatically decrease palladium leaching in Suzuki couplings

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 May 2012, accepted on 19 Jul 2012 and first published on 24 Jul 2012


Article type: Paper
DOI: 10.1039/C2GC35832H
Citation: Green Chem., 2012,14, 2807-2815
  •   Request permissions

    An efficient and recyclable dendritic catalyst able to dramatically decrease palladium leaching in Suzuki couplings

    M. Keller, A. Hameau, G. Spataro, S. Ladeira, A. Caminade, J. Majoral and A. Ouali, Green Chem., 2012, 14, 2807
    DOI: 10.1039/C2GC35832H

Search articles by author

Spotlight

Advertisements