Issue 2, 2012

Recent advances in transition metal-catalyzed sp3 C–H amination adjacent to double bonds and carbonyl groups

Abstract

Transition metal-catalyzed C–H amination at positions adjacent to double bonds and carbonyl groups is discussed in this critical review. While the focus will center on the recent developments of α-oxidative amination, some historical developments and mutually beneficial reports in the broader field of C–H amination will be discussed. C–H amination has become a viable method for the efficient installation of nitrogen atoms en route to target molecules (89 references).

Graphical abstract: Recent advances in transition metal-catalyzed sp3 C–H amination adjacent to double bonds and carbonyl groups

Article information

Article type
Critical Review
Submitted
15 Apr 2011
First published
15 Aug 2011

Chem. Soc. Rev., 2012,41, 931-942

Recent advances in transition metal-catalyzed sp3 C–H amination adjacent to double bonds and carbonyl groups

T. A. Ramirez, B. Zhao and Y. Shi, Chem. Soc. Rev., 2012, 41, 931 DOI: 10.1039/C1CS15104E

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