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Issue 90, 2012
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A DNA based five-state switch with programmed reversibility

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Abstract

A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrinporphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

Graphical abstract: A DNA based five-state switch with programmed reversibility

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Publication details

The article was received on 10 Aug 2012, accepted on 21 Sep 2012 and first published on 24 Sep 2012


Article type: Communication
DOI: 10.1039/C2CC35799B
Chem. Commun., 2012,48, 11088-11090
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    A DNA based five-state switch with programmed reversibility

    J. R. Burns, S. Preus, D. G. Singleton and E. Stulz, Chem. Commun., 2012, 48, 11088
    DOI: 10.1039/C2CC35799B

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