Issue 44, 2012

Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

Abstract

A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.

Graphical abstract: Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

Supplementary files

Article information

Article type
Communication
Submitted
24 Mar 2012
Accepted
12 Apr 2012
First published
12 Apr 2012

Chem. Commun., 2012,48, 5434-5436

Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters

T. Ohshima, Y. Hayashi, K. Agura, Y. Fujii, A. Yoshiyama and K. Mashima, Chem. Commun., 2012, 48, 5434 DOI: 10.1039/C2CC32153J

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