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Issue 66, 2012
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Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

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Abstract

G-quadruplex conformations within a sequence of three quadruplex units of human telomeric DNA were studied by two-frequency pulsed electron paramagnetic resonance (EPR) spectroscopy. In contrast to some individual G-quadruplexes, within the higher-order human telomeric sequence a (3+1) hybrid structure is formed.

Graphical abstract: Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

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Publication details

The article was received on 19 Mar 2012, accepted on 10 Apr 2012 and first published on 10 Apr 2012


Article type: Communication
DOI: 10.1039/C2CC32012F
Citation: Chem. Commun., 2012,48, 8258-8260

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    Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

    V. Singh, M. Azarkh, M. Drescher and J. S. Hartig, Chem. Commun., 2012, 48, 8258
    DOI: 10.1039/C2CC32012F

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