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Issue 51, 2012
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An ultrasensitive electrochemical impedance sensor for a special BRCA1 breast cancer gene sequence based on lambda exonuclease assisted target recycling amplification

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Abstract

A label-free, target recycling electrochemical impedance spectroscopy (EIS) DNA sensor has been developed for detection of a model related to the BRCA1 breast cancer gene with a detection limit of 0.05 nM.

Graphical abstract: An ultrasensitive electrochemical impedance sensor for a special BRCA1 breast cancer gene sequence based on lambda exonuclease assisted target recycling amplification

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Supplementary files

Article information


Submitted
02 Mar 2012
Accepted
20 Apr 2012
First published
20 Apr 2012

Chem. Commun., 2012,48, 6390-6392
Article type
Communication

An ultrasensitive electrochemical impedance sensor for a special BRCA1 breast cancer gene sequence based on lambda exonuclease assisted target recycling amplification

H. Xu, L. Wang, H. Ye, L. Yu, X. Zhu, Z. Lin, G. Wu, X. Li, X. Liu and G. Chen, Chem. Commun., 2012, 48, 6390
DOI: 10.1039/C2CC31588B

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