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Issue 21, 2012
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Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

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Abstract

A novel iron-catalysed tandem cross-dehydrogenative coupling and benzoannulation process was developed for the synthesis of biologically and synthetically important polysubstituted naphthalene derivatives from simple 1,2-aryl-propenes and styrenes in moderate to good yields.

Graphical abstract: Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

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Publication details

The article was received on 24 Nov 2011, accepted on 12 Jan 2012 and first published on 16 Jan 2012


Article type: Communication
DOI: 10.1039/C2CC17330A
Citation: Chem. Commun., 2012,48, 2674-2676
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    Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes

    H. Liu, L. Cao, J. Sun, J. S. Fossey and W. Deng, Chem. Commun., 2012, 48, 2674
    DOI: 10.1039/C2CC17330A

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