The hyperthermophile Pyrococcus furiosus catalyses the hydrogenation of a broad range of carboxylic acids selectively to the corresponding primary alcohols. Other functional groups such as isolated C![[double bond, length as m-dash]](https://www.rsc.org/images/entities/char_e001.gif)
C-double bonds are not touched. The chemoselectivity of the carboxylate reduction may be directed towards aldehydes by simple medium engineering.
Y. Ni, P. Hagedoorn, J. Xu, I. W. C. E. Arends and F. Hollmann, Chem. Commun., 2012, 48, 12056 DOI: 10.1039/C2CC36479D
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