Issue 90, 2012
From the journal:

Chemical Communications

An enzyme-responsive nanocontainer as an intelligent signal-amplification platform for a multiple proteases assay†

Xinjian Yang,ab   Fang Pu,a   Cuie Chen,a   Jinsong Ren*a  and  Xiaogang Qua  

* Corresponding authors

a State Key Laboratory of Rare Earth Resources Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: jren@ciac.jl.cn

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

Abstract

Based on selective pore-opening in the presence of protease, we have developed a novel signal amplification assay for multiple proteases detection and their inhibition using protein-capped mesoporous scaffolding as the substrate.

Graphical abstract: An enzyme-responsive nanocontainer as an intelligent signal-amplification platform for a multiple proteases assay

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Article information

DOI
https://doi.org/10.1039/C2CC36340B
Article type
Communication
Submitted
31 Aug 2012
Accepted
26 Sep 2012
First published
27 Sep 2012

Chem. Commun., 2012,48, 11133-11135

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An enzyme-responsive nanocontainer as an intelligent signal-amplification platform for a multiple proteases assay

X. Yang, F. Pu, C. Chen, J. Ren and X. Qu, Chem. Commun., 2012, 48, 11133 DOI: 10.1039/C2CC36340B

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