Design of highly potent HIV fusion inhibitors based on artificial peptide sequences†
Abstract
Specific interactions were introduced between an artificial heptad repeat peptide template and HIV-1 gp41 for fusion
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* Corresponding authors
a
Department of Medicinal Chemistry, Beijing Institute of Pharmacology & Toxicology, 27 Taiping Rd, Haidian District, Beijing 100850, China
E-mail:
keliangliu55@126.com
Fax: +86-10-68211656
b
Key Lab of Medical Molecular Virology (Ministries of Education and Health), Shanghai Medical College and Institute of Medical Microbiology, Fudan University 130 Dong An Road, Xuhui District, Shanghai 200032, China
E-mail:
shibojiang@fudan.edu.cn
Fax: +86-21-54237465
Specific interactions were introduced between an artificial heptad repeat peptide template and HIV-1 gp41 for fusion
W. Shi, L. Cai, L. Lu, C. Wang, K. Wang, L. Xu, S. Zhang, H. Han, X. Jiang, B. Zheng, S. Jiang and K. Liu, Chem. Commun., 2012, 48, 11579 DOI: 10.1039/C2CC35973A
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