Issue 87, 2012

Intermolecular G-quadruplex-based universal quencher free molecular beacon

Abstract

A simple and universal quencher-free molecular beacon (MB) with low background fluorescence is developed based on an intermolecular G-quadruplex signaling probe. Unlike previous fluorescent MB strategies, it can function without any fluorophore and quencher modifications on its hairpin sequence.

Graphical abstract: Intermolecular G-quadruplex-based universal quencher free molecular beacon

Supplementary files

Article information

Article type
Communication
Submitted
17 Aug 2012
Accepted
12 Sep 2012
First published
13 Sep 2012

Chem. Commun., 2012,48, 10760-10762

Intermolecular G-quadruplex-based universal quencher free molecular beacon

H. Zhou, S. Xie, J. Li, Z. Wu and G. Shen, Chem. Commun., 2012, 48, 10760 DOI: 10.1039/C2CC35964B

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