Issue 78, 2012

Chemoenzymatic preparation of germacrene analogues


A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.

Graphical abstract: Chemoenzymatic preparation of germacrene analogues

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Article information

Article type
31 Jul 2012
14 Aug 2012
First published
15 Aug 2012
This article is Open Access
Creative Commons BY license

Chem. Commun., 2012,48, 9702-9704

Chemoenzymatic preparation of germacrene analogues

O. Cascón, S. Touchet, D. J. Miller, V. Gonzalez, J. A. Faraldos and R. K. Allemann, Chem. Commun., 2012, 48, 9702 DOI: 10.1039/C2CC35542F

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