Here we report an electrochemical DNA (E-DNA) chiral sensor that can distinguish zinc-finger like metallo-supramolecular enantiomers based on human telomeric G-quadruplex formation specifically induced by one of the enantiomers. The assay is easy to operate and reusable with an enantioselective recognition ratio higher than 5.
L. Feng, B. Xu, J. Ren, C. Zhao and X. Qu, Chem. Commun., 2012, 48, 9068 DOI: 10.1039/C2CC34776H
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