Issue 74, 2012

GOx signaling triggered by aptamer-based ATP detection

Abstract

Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to ‘turn-on’ the activity of apo-GOx and thus generates a measurable response.

Graphical abstract: GOx signaling triggered by aptamer-based ATP detection

Supplementary files

Article information

Article type
Communication
Submitted
14 Jun 2012
Accepted
27 Jul 2012
First published
27 Jul 2012

Chem. Commun., 2012,48, 9284-9286

GOx signaling triggered by aptamer-based ATP detection

S. Sitaula, S. D. Branch and M. F. Ali, Chem. Commun., 2012, 48, 9284 DOI: 10.1039/C2CC34279K

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