Issue 80, 2012
From the journal:

Chemical Communications

Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with β-cyclodextrin-modified hollow mesoporous silicananoparticles for controlled drug release†

Xiao Mei,a   Shun Yang,a   Dongyun Chen,a   Najun Li,*a   Hua Li,a   Qingfeng Xu,a   Jianfeng Gea  and  Jianmei Lu*a  

* Corresponding authors

a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, P. R. China
E-mail: lujm@suda.edu.cn, linajun@suda.edu.cn
Fax: +86 512 6588 0367
Tel: +86 512 6588 0368

Abstract

Hollow mesoporous silica nanoparticles (HMSs) were modified by β-cyclodextrin via a “click” reaction, an amphiphilic copolymer with a trans-azobenzene structure was then assembled onto β-cyclodextrin to cover the surface of the HMSs. The prepared nanocomposites can release drugs in a “release-stop-release” manner by converting light irradiation.

Graphical abstract: Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with β-cyclodextrin-modified hollow mesoporous silica nanoparticles for controlled drug release

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Article information

DOI
https://doi.org/10.1039/C2CC33995A
Article type
Communication
Submitted
04 Jun 2012
Accepted
21 Aug 2012
First published
22 Aug 2012

Chem. Commun., 2012,48, 10010-10012

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Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with β-cyclodextrin-modified hollow mesoporous silica nanoparticles for controlled drug release

X. Mei, S. Yang, D. Chen, N. Li, H. Li, Q. Xu, J. Ge and J. Lu, Chem. Commun., 2012, 48, 10010 DOI: 10.1039/C2CC33995A

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