Issue 61, 2012
From the journal:

Chemical Communications

Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone–boronic acid hybrids†

Daisuke Takahashi,a   Takuya Miuraa  and  Kazunobu Toshima*a  

* Corresponding authors

a Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan
E-mail: toshima@applc.keio.ac.jp
Fax: +81 45-566-1576

Abstract

Target-selective photodegradation of 3-deoxy-D-manno-2-octulopyranosonic acid (KDO) was achieved without additives and under neutral conditions using a designed anthraquinone–boronic acid hybrid and long wavelength UV light irradiation. The hybrid can photodegrade lipopolysaccharides (LPS) and inhibit macrophage activation induced by LPS.

Graphical abstract: Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone–boronic acid hybrids

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC33559J
Article type
Communication
Submitted
17 May 2012
Accepted
07 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 7595-7597

Permissions

Request permissions

Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone–boronic acid hybrids

D. Takahashi, T. Miura and K. Toshima, Chem. Commun., 2012, 48, 7595 DOI: 10.1039/C2CC33559J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements