Issue 61, 2012
From the journal:

Chemical Communications

Scanometric analysis of DNA microarrays using DNA intercalator-conjugated gold nanoparticles†

Hyunmin Cho,ab   Juyeon Junga  and  Bong Hyun Chung*ab  

* Corresponding authors

a Bio Nanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yuseong, Republic of Korea
E-mail: chungbh@kribb.re.kr
Fax: +82-42-879-8594

b Nanobiotechnology, School of Engineering, University of Science and Technology (UST), P.O. Box 115, Yuseong, Republic of Korea

Abstract

We introduce a scanometric detection method for the analysis of DNA microarrays using DNA intercalator-conjugated gold nanoparticles that can be analyzed with the naked eye or with an optical scanner after the enhancement of the AuNPs. Moreover, we successfully detected a hemagglutinin-subtyping DNA array using this method.

Graphical abstract: Scanometric analysis of DNA microarrays using DNA intercalator-conjugated gold nanoparticles

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Article information

DOI
https://doi.org/10.1039/C2CC32869K
Article type
Communication
Submitted
23 Apr 2012
Accepted
15 Jun 2012
First published
19 Jun 2012

Chem. Commun., 2012,48, 7601-7603

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Scanometric analysis of DNA microarrays using DNA intercalator-conjugated gold nanoparticles

H. Cho, J. Jung and B. H. Chung, Chem. Commun., 2012, 48, 7601 DOI: 10.1039/C2CC32869K

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