Issue 28, 2012

Enantioselective synthesis of (−)-paeonilide

Abstract

The first enantioselective synthesis of (−)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.

Graphical abstract: Enantioselective synthesis of (−)-paeonilide

Supplementary files

Article information

Article type
Communication
Submitted
30 Dec 2011
Accepted
09 Feb 2012
First published
23 Feb 2012

Chem. Commun., 2012,48, 3457-3459

Enantioselective synthesis of (−)-paeonilide

K. Harrar and O. Reiser, Chem. Commun., 2012, 48, 3457 DOI: 10.1039/C2CC18172J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements