Issue 27, 2012
From the journal:

Chemical Communications

Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA†

Jin Xu,a   Bingying Jiang,b   Jiao Su,a   Yun Xiang,*a   Ruo Yuana  and  Yaqin Chaia  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

b School of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400054, P. R. China

Abstract

By using exonuclease I and biobarcode nanoparticles, we describe a novel background current reduction strategy for amplified electrochemical detection of uropathogen specific sequences at ultralow concentrations.

Graphical abstract: Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA

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Article information

DOI
https://doi.org/10.1039/C2CC18107J
Article type
Communication
Submitted
28 Dec 2011
Accepted
07 Feb 2012
First published
23 Feb 2012

Chem. Commun., 2012,48, 3309-3311

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Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA

J. Xu, B. Jiang, J. Su, Y. Xiang, R. Yuan and Y. Chai, Chem. Commun., 2012, 48, 3309 DOI: 10.1039/C2CC18107J

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