Issue 21, 2012

An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

Abstract

An aptamer microarray was directly fabricated on a MALDI target plate for high-throughput insulin detection. High sensitivities were observed both in standard solutions (5 ng mL−1, 0.86 nM) and serum sample (20 ng mL−1, 3.4 nM). This method shows great promise in the field of biomarker detection.

Graphical abstract: An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

Supplementary files

Article information

Article type
Communication
Submitted
21 Dec 2011
Accepted
19 Jan 2012
First published
20 Jan 2012

Chem. Commun., 2012,48, 2689-2691

An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS

X. Zhang, S. Zhu, C. Deng and X. Zhang, Chem. Commun., 2012, 48, 2689 DOI: 10.1039/C2CC17997K

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