Issue 4, 2012

Probing the limitations of the fluorous content for tag-mediated microarray formation

Abstract

The synthesis of a di-perfluorohexyl tag is reported for use in a fluorous-based carbohydrate microarray. A comparative microarray study with this di-perfluorohexyl tag and a mono-perfluorooctyl and mono-perfluorohexyl tag found the increased fluorous content conducive to better spot morphology and easier washing protocols without precluding reuse of the fluorous slide.

Graphical abstract: Probing the limitations of the fluorous content for tag-mediated microarray formation

Supplementary files

Article information

Article type
Communication
Submitted
27 Sep 2011
Accepted
15 Nov 2011
First published
29 Nov 2011

Chem. Commun., 2012,48, 510-512

Probing the limitations of the fluorous content for tag-mediated microarray formation

H. D. Edwards, S. K. Nagappayya and N. L. B. Pohl, Chem. Commun., 2012, 48, 510 DOI: 10.1039/C1CC16022B

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