Issue 7, 2012
From the journal:

Chemical Communications

Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides†

Hongqiang Qin,a   Fangjun Wang,a   Peiyuan Wang,b   Liang Zhao,a   Jun Zhu,a   Qihua Yang,b   Ren'an Wu,a   Mingliang Yea  and  Hanfa Zou*a  

* Corresponding authors

a CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China
E-mail: hanfazou@dicp.ac.cn

b State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China

Abstract

Ti4+-EPO nanoparticles were adopted as the adsorbent for in situ solid phase enrichment and isotope labeling of endogenous phosphopeptides, which has great potential application in high-throughput analyses of biological samples for screening and discovery of disease-specific biomarkers.

Graphical abstract: Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides

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Article information

DOI
https://doi.org/10.1039/C1CC15222J
Article type
Communication
Submitted
23 Aug 2011
Accepted
18 Oct 2011
First published
03 Nov 2011

Chem. Commun., 2012,48, 961-963

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Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides

H. Qin, F. Wang, P. Wang, L. Zhao, J. Zhu, Q. Yang, R. Wu, M. Ye and H. Zou, Chem. Commun., 2012, 48, 961 DOI: 10.1039/C1CC15222J

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