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Issue 4, 2012
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Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

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Abstract

We developed a new o-phenylenediamine-based compound as a turn-on fluorescent probe for nitric oxide (NO) with a large blue shift in absorption. It showed high selectivity and sensitivity toward nitric oxide over other ROS and RNS species in neutral buffer solution. The analytical detection limit (ADL) was 30 nM. As far as we are aware this is the first o-phenylenediamine-based NO probe using Cu2+ as a promoter.

Graphical abstract: Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

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Publication details

The article was received on 12 Jan 2012, accepted on 19 Feb 2012 and first published on 16 Mar 2012


Article type: Paper
DOI: 10.1039/C2AY25039J
Citation: Anal. Methods, 2012,4, 919-922
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    Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

    X. Sun, Y. Xu, W. Zhu, C. He, L. Xu, Y. Yang and X. Qian, Anal. Methods, 2012, 4, 919
    DOI: 10.1039/C2AY25039J

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