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Issue 7, 2011
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Ammonium ylides for the diastereoselective synthesis of glycidic amides

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Abstract

A highly trans-selective protocol for the synthesis of glycidic amides was developed. This approach gave access to oxiranes by reacting stabilised ammonium ylides bearing an α-carbonyl group and aromatic aldehydes in moderate to good yields.

Graphical abstract: Ammonium ylides for the diastereoselective synthesis of glycidic amides

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Supplementary files

Article information


Submitted
05 Nov 2010
Accepted
30 Nov 2010
First published
21 Dec 2010

This article is Open Access

Chem. Commun., 2011,47, 2170-2172
Article type
Communication

Ammonium ylides for the diastereoselective synthesis of glycidic amides

M. Waser, R. Herchl and N. Müller, Chem. Commun., 2011, 47, 2170
DOI: 10.1039/C0CC04821F

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