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Issue 23, 2011
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Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

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Abstract

Dual fluorescent micelles with a hydrophobic probe (HMA) embedded in the micelle core and a hydrophilic probe (TRITC) attached on the micelle corona were prepared. These micelles can act as nanometre-sized thermal sensors. Within a short temperature range, the fluorescent emission of the micelles changes strongly and reversibly as a function of temperature. These micelles can be easily taken up by human HeLa cells and can potentially be used as intracellular thermometers.

Graphical abstract: Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

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Publication details

The article was received on 22 Aug 2011, accepted on 09 Sep 2011 and first published on 14 Oct 2011


Article type: Paper
DOI: 10.1039/C1SM06597A
Citation: Soft Matter, 2011,7, 11211-11215
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    Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

    F. Li, A. H. Westphal, A. T. M. Marcelis, E. J. R. Sudhölter, M. A. Cohen Stuart and F. A. M. Leermakers, Soft Matter, 2011, 7, 11211
    DOI: 10.1039/C1SM06597A

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