Issue 13, 2011

An efficient route to 1-aminoisoquinolines viaAgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine

Abstract

2-Alkynylbenzaldoxime reacts with amine catalyzed by silver triflate under mild conditions, leading to 1-aminoisoquinolines in good yield. This reaction proceeds efficiently with good functional group tolerance.

Graphical abstract: An efficient route to 1-aminoisoquinolines viaAgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine

Supplementary files

Article information

Article type
Communication
Submitted
12 Apr 2011
Accepted
12 May 2011
First published
13 May 2011

Org. Biomol. Chem., 2011,9, 4763-4765

An efficient route to 1-aminoisoquinolines viaAgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine

D. Zheng, Z. Chen, J. Liu and J. Wu, Org. Biomol. Chem., 2011, 9, 4763 DOI: 10.1039/C1OB05582H

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