Issue 10, 2011
From the journal:

Organic & Biomolecular Chemistry

Enantioselective organocatalytic Michael-hemiketalization catalyzed by a trans-bifunctional indanethioureacatalyst†

Yaojun Gao,a   Qiao Ren,a   Swee-Meng Anga  and  Jian Wang*a  

* Corresponding authors

a Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore
E-mail: chmwangj@nus.edu.sg
Fax: (+)65-6516-1691

Abstract

An efficient, convenient and enantioselective Michael-hemiketalization reaction has been developed for the synthesis of naphthoquinones. In this work, a novel trans-bifunctional indane thiourea catalyst has been reported to promote this process to afford high yields (up to 99%) and high to excellent enantiomeric excesses (90–98% ee).

Graphical abstract: Enantioselective organocatalytic Michael-hemiketalization catalyzed by a trans-bifunctional indane thiourea catalyst

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1OB05404J
Article type
Paper
Submitted
15 Mar 2011
Accepted
23 Mar 2011
First published
23 Mar 2011

Org. Biomol. Chem., 2011,9, 3691-3697

Permissions

Request permissions

Enantioselective organocatalytic Michael-hemiketalization catalyzed by a trans-bifunctional indane thiourea catalyst

Y. Gao, Q. Ren, S. Ang and J. Wang, Org. Biomol. Chem., 2011, 9, 3691 DOI: 10.1039/C1OB05404J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements