Issue 14, 2011
From the journal:

Organic & Biomolecular Chemistry

CuBr Catalyzed C–N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines†

Hong-Ying Niu,ab   Chao Xia,a   Gui-Rong Qu,*a   Qian Zhang,a   Yi Jiang,a   Run-Ze Mao,a   De-Yang Lia  and  Hai-Ming Guo*a  

* Corresponding authors

a College of Chemistry and Environmental Science, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, China
E-mail: guohm518@hotmail.com, quguir@sina.com
Fax: 86 373 3329276

b School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang, China

Abstract

CuBr was found to be an efficient catalyst for the C–N cross coupling reaction of purine and diaryliodonium salts. 9-Arylpurines were synthesized in excellent yields with short reaction times (2.5 h). The method represents an alternative to the synthesis of 9-arylpurines viaCu(II) catalyzed C–N coupling reaction with arylboronic acids as arylating agents.

Graphical abstract: CuBr Catalyzed C–N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1OB05333G
Article type
Communication
Submitted
03 Mar 2011
Accepted
20 May 2011
First published
23 May 2011

Org. Biomol. Chem., 2011,9, 5039-5042

Permissions

Request permissions

CuBr Catalyzed C–N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines

H. Niu, C. Xia, G. Qu, Q. Zhang, Y. Jiang, R. Mao, D. Li and H. Guo, Org. Biomol. Chem., 2011, 9, 5039 DOI: 10.1039/C1OB05333G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements