Issue 15, 2011
From the journal:

Organic & Biomolecular Chemistry

Target-selective fluorescent “switch-on” proteinlabeling by 6π-azaelectrocyclization†

Katsunori Tanaka,*a   Masataka Kitadania  and  Koichi Fukase*a  

* Corresponding authors

a Address, Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka, Japan
E-mail: ktzenori@chem.sci.osaka-u.ac.jp, koichi@chem.sci.osaka-u.ac.jp
Fax: +81-6-6850-5419
Tel: +81-6-6850-5391

Abstract

Application of azaelectrocyclization and FRET techniques to lysine groups enabled the selective and sensitive detection of a target protein from a mixture, with high fluorescence contrast.

Graphical abstract: Target-selective fluorescent “switch-on” protein labeling by 6π-azaelectrocyclization

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Article information

DOI
https://doi.org/10.1039/C1OB05320E
Article type
Communication
Submitted
28 Feb 2011
Accepted
03 Jun 2011
First published
06 Jun 2011

Org. Biomol. Chem., 2011,9, 5346-5349

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Target-selective fluorescent “switch-on” protein labeling by 6π-azaelectrocyclization

K. Tanaka, M. Kitadani and K. Fukase, Org. Biomol. Chem., 2011, 9, 5346 DOI: 10.1039/C1OB05320E

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