Stereoselective synthesis of the C15–C26 fragment of the antitumor agent (−)-dictyostatin†
Abstract
The synthesis of the C15–C26 fragment of (−)-dictyostatin is reported in 10 steps and 28% overall yield. The key steps are the two stereoselective
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* Corresponding authors
a
Departamento de Química Orgánica (Módulo 01), Universidad Autónoma de Madrid, Madrid, Spain
E-mail:
antonio.urbano@uam.es, carmen.carrenno@uam.es
b Laboratoire de Stéréochimie, Université de Strasbourg, ECPM 25 rue Becquerel, Strasbourg Cedex 2, France
The synthesis of the C15–C26 fragment of (−)-dictyostatin is reported in 10 steps and 28% overall yield. The key steps are the two stereoselective
L. Ferreiro-Mederos, S. Vila-Gisbert, A. Urbano, M. C. Carreño and F. Colobert, Org. Biomol. Chem., 2011, 9, 758 DOI: 10.1039/C0OB00491J
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