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Issue 7, 2011
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Silver nanoparticle studded porous polyethylene scaffolds: bacteria struggle to grow on them while mammalian cells thrive

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Abstract

Silver nanoparticle studded scaffolds were prepared by exploiting the Ag+ ion reducing activity of sophorolipids—a class of ‘glycolipids’ that cap the ensuing nanoparticles as well. To achieve this, the porous polyethylene scaffolds are subjected to N2 + H2 plasma treatment, in the first step. Subsequently the sophorolipids are covalently attached to the amine groups on the polymer surface through simple amide chemistry to yield sophorolipid grafted polymer scaffolds. These are then exposed to Ag+ ions under appropriate conditions leading to the formation of silver nanoparticles immobilized on the polymer scaffolds. It has been found that while bacteria do not survive on these silver studded scaffolds, CHO-K1 cells thrive on them making them good candidates for tissue engineering and bio-implant applications.

Graphical abstract: Silver nanoparticle studded porous polyethylene scaffolds: bacteria struggle to grow on them while mammalian cells thrive

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Supplementary files

Article information


Submitted
11 Feb 2011
Accepted
19 Apr 2011
First published
03 Jun 2011

Nanoscale, 2011,3, 2957-2963
Article type
Paper

Silver nanoparticle studded porous polyethylene scaffolds: bacteria struggle to grow on them while mammalian cells thrive

V. D'Britto, H. Kapse, H. Babrekar, A. A. Prabhune, S. V. Bhoraskar, V. Premnath and B. L. V. Prasad, Nanoscale, 2011, 3, 2957
DOI: 10.1039/C1NR10154D

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