Issue 2, 2011

Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications

Abstract

In recent years, nanomaterials have captured the attention of scientists from a wide spectrum of domains. With their unique properties, nanomaterials offer great promise for numerous applications, ranging from catalysis to energy harvesting and information technology. Functionalized with the desired biomolecules, nanomaterials can also be utilized for many biomedical applications. This paper summarizes recent achievements in the use of aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications. First, we discuss the features and properties of aptamers and then illustrate the use of aptamer-conjugated nanomaterials as sensing platforms and delivery vehicles, emphasizing how such integration can result in enhanced sensitivity and selectivity.

Graphical abstract: Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications

Article information

Article type
Minireview
Submitted
01 Sep 2010
Accepted
09 Oct 2010
First published
25 Nov 2010

Nanoscale, 2011,3, 546-556

Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications

T. Chen, M. I. Shukoor, Y. Chen, Q. Yuan, Z. Zhu, Z. Zhao, B. Gulbakan and W. Tan, Nanoscale, 2011, 3, 546 DOI: 10.1039/C0NR00646G

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