Issue 4, 2011
From the journal:

Natural Product Reports

Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi

Erika Izumi,a   Tânia Ueda-Nakamura,b   Benedito Prado Dias Filho,ab   Valdir Florêncio Veiga Júniorc  and  Celso Vataru Nakamura*ab  

* Corresponding authors

a Programa de Pós-Graduação em Microbiologia, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid s/n, Londrina-PR, Brazil
E-mail: cvnakamura@uem.br
Fax: +55 44 3011-5050
Tel: +55 44 3041-5012

b Departamento de Ciências Básicas da Saúde, Laboratório de Inovação Tecnológica no Desenvolvimento de Fármacos e Cosméticos, Universidade Estadual de Maringá, Av. Colombo 5790, Maringá-PR, Brazil

c Departamento de Química, Instituto de Ciências Exatas, Universidade Federal do Amazonas, Av. Gal. Rodrigo Octávio Jordão Ramos 3000, Japiim, Manaus, Brazil

Abstract

Covering: 1995 to 2010

Here, we review studies that have investigated the activity of plant-derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas' disease. In the last decade, more than 300 species belonging to almost 100 families have been evaluated for activity, and here we describe the compounds isolated; 85 references are cited.

Graphical abstract: Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi

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Article information

DOI
https://doi.org/10.1039/C0NP00069H
Article type
Review Article
Submitted
31 May 2010
First published
03 Feb 2011

Nat. Prod. Rep., 2011,28, 809-823

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Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi

E. Izumi, T. Ueda-Nakamura, B. P. Dias Filho, V. F. Veiga Júnior and C. V. Nakamura, Nat. Prod. Rep., 2011, 28, 809 DOI: 10.1039/C0NP00069H

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