Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ†
Abstract
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* Corresponding authors
a
Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo 1, Perugia, Italy
E-mail:
rp@unipg.it
Fax: +39 075 5855124
Tel: +39 075 5855120
b Pfizer Global Research and Development, Neuroscience Research Unit, 558 Eastern Point Road, Groton, CT, USA
c Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, V.le Pieraccini 6, Firenze, Italy
d Dipartimento Farmaceutico, Università di Parma, V.le G.P. Usberti 27/A, Parma, Italy
e Pfizer Global Research and Development, Global Biotherapeutic Technologies, 200 Cambridgepark Drive, Cambridge, MA
R. Pellicciari, E. Camaioni, A. M. Gilbert, A. Macchiarulo, J. A. Bikker, F. Shah, J. Bard, G. Costantino, A. Gioiello, G. M. Robertson, P. Sabbatini, F. Venturoni, P. Liscio, A. Carotti, D. Bellocchi, A. Cozzi, A. Wood, C. Gonzales, M. M. Zaleska, J. W. Ellingboe and F. Moroni, Med. Chem. Commun., 2011, 2, 559 DOI: 10.1039/C1MD00021G
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