Issue 6, 2011

Diacrylamides as selective G-quadruplex ligands in in vitro and in vivo assays

Abstract

The synthesis of previously unreported anthracene-9-monoacrylamides and anthracen-9,10-bisacrylamides and their potential as G-quadruplex ligands, based on preliminary fluorometric and biological assay data, is discussed.

Graphical abstract: Diacrylamides as selective G-quadruplex ligands in in vitro and in vivo assays

Supplementary files

Article information

Article type
Concise Article
Submitted
19 Jan 2011
Accepted
07 Mar 2011
First published
23 Mar 2011

Med. Chem. Commun., 2011,2, 466-470

Diacrylamides as selective G-quadruplex ligands in in vitro and in vivo assays

A. Le Gresley, A. Abdullah, D. Chawla, P. Desai, U. Ghosh, U. Gollapalli, M. Kiran, S. Lafon and A. Sinclair, Med. Chem. Commun., 2011, 2, 466 DOI: 10.1039/C1MD00020A

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